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A pregnant woman's sudden blindness turned out to be a rare brain tumor. A 39-year-old at 26 weeks' gestation lost vision in her left eye and was found to have a 2.2-cm meningioma compressing her optic nerve. Emergency surgery restored partial vision — and highlights how pregnancy can rapidly accelerate these tumors.
A 39-year-old woman at 26 weeks' gestation woke from a nap with complete vision loss in her left eye. Already managing pregestational diabetes, obesity, and preeclampsia, she had also been experiencing months of worsening left-sided headaches — symptoms easily mistaken for routine pregnancy discomfort. An MRI revealed a 2.2-cm suprasellar mass compressing her left optic nerve, ultimately diagnosed as a grade II atypical clear cell tuberculum sella meningioma.
Meningiomas are the most common primary brain tumor in adults, with a 3:1 female-to-male ratio during reproductive years. Pregnancy can accelerate their growth through hormonal (progesterone receptor-driven) and hemodynamic mechanisms, turning a slow-growing tumor into a sight-threatening emergency. The patient underwent urgent neurosurgical decompression the day after imaging, with partial vision recovery noted by postoperative day 1.
Key Takeaways:
Why it matters: This case is a reminder that vision loss in pregnancy should never be dismissed as routine. Early recognition and urgent surgical intervention can be the difference between preserved and permanently lost sight.