
A new CTLA-4 drug is turning heads in hard-to-treat lung cancer
For patients with advanced squamous lung cancer who've already tried immunotherapy, options have been slim for a decade — but that may be changing. Updated data from the PRESERVE-003 trial show that gotistobart, a next-generation CTLA-4 antibody, nearly doubled median overall survival compared to standard chemotherapy. Experts are cautiously optimistic, though they stress the need for proactive toxicity management and broader genomic testing.
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