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Space-proofing cataract surgery: As long-duration space missions become a reality, researchers are figuring out how to safely transport intraocular lenses (IOLs) beyond Earth. A study exposed 135 IOLs to the harsh exterior of the ISS for 6 months, finding that lenses closer to open space suffered more damage — including cracks, yellowing, and reduced light transmission — while shielded lenses fared much better.
Space-proofing cataract surgery: IOLs face the final frontier
With Mars missions on the horizon, researchers are tackling a surprisingly practical question: what happens to intraocular lenses (IOLs) in space? Dr. J. Morgan Micheletti and his team sent 135 IOLs to the exterior of the International Space Station (ISS) for 6 months, testing how different exposure conditions affect lens integrity — a critical step toward enabling cataract surgery on long-duration missions.
The lenses were placed on three carriers in distinct locations: forward-facing (high atomic oxygen), solar-facing (high UV radiation), and "underdeck" (partially shielded). Results showed that the closer the lenses were to open space, the more damage they sustained. Notably, Light Adjustable Lenses (RxSight) developed a distinctive cobblestone pattern regardless of placement, suggesting a unique vulnerability.
By the Numbers
Why it matters: As space travel extends to multi-year missions, medical readiness — including eye care — becomes essential. This research lays the groundwork for determining minimum shielding requirements for surgical supplies, helping ensure astronauts can receive critical care far from Earth.
