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Unemployed and retired patients with type 2 diabetes and heart disease are significantly less likely to be prescribed cardioprotective medications like SGLT2 inhibitors and GLP-1 receptor agonists, a large Danish study finds. Marital status also played a role, while education level had no independent effect. The findings point to deep socioeconomic gaps in access to evidence-based care.
A nationwide Danish cohort study of over 81,000 adults with newly diagnosed type 2 diabetes (T2D) and cardiovascular disease (CVD) found that employment status is a major predictor of whether patients receive guideline-recommended cardioprotective medications. Unemployed and retired patients — both men and women — were significantly less likely to start SGLT2 inhibitors or GLP-1 receptor agonists compared to their employed counterparts. Marital status also mattered, with unmarried, divorced, or widowed patients showing lower initiation rates.
Of the full cohort, only about 30% (24,623 patients) started a cardioprotective drug during follow-up, with SGLT2 inhibitors being the more commonly chosen option. Older age, newly diagnosed diabetes, and lower A1c levels were also linked to a higher likelihood of not starting these therapies — suggesting that patients perceived as lower-risk may be systematically undertreated.
By the Numbers:
Why it matters: These findings expose a troubling equity gap in cardiovascular diabetes care. Socioeconomic factors — not just clinical ones — are shaping who gets life-saving medications, underscoring the urgent need for systemic reforms in prescribing practices, cost coverage, and healthcare delivery.