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Healthcare startup Zus Health has secured $33M in Series B funding to build the connected patient data infrastructure that AI clinical tools need to function reliably. Founded by Jonathan Bush, the company aggregates fragmented patient records into a unified, continuously updated longitudinal profile. The goal: make AI-powered care workflows faster, smarter, and more usable at the point of care.
As healthcare companies rush to build AI copilots and agents, Zus Health is making a different bet — that the real opportunity lies in the data infrastructure underneath those tools. The Boston-based startup, founded by Jonathan Bush, just closed a $33M Series B led by Drive Capital, with participation from Sanofi Ventures, a16z, and others. The fresh capital brings total funding to over $100M.
Zus's platform works in three layers: a nationwide patient record, a data network that continuously feeds it, and AI-powered workflows that automate care tasks using that richer data. Its flagship product, the Zus Aggregated Profile (ZAP), pulls fragmented clinical data from EHRs, pharmacies, labs, and care event notifications into a single longitudinal record — no manual reconciliation required. The company is growing fast, especially in specialty care like oncology, where patient records are notoriously scattered across providers.
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Why it matters: EHRs digitized healthcare but never made data truly portable. Zus is betting that reliable, connected patient data is the missing piece that will determine which AI healthcare tools actually succeed — and which ones stall out on incomplete inputs.