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A new review of 41 studies published in PLOS One finds that women are less likely than men to receive active or invasive medical treatment for the same conditions — and this pattern holds across specialties from cardiology to emergency medicine. Researchers say the disparity is persistent but its clinical impact remains unclear. The team now plans to examine whether AI systems trained on this biased data could further entrench the gap.
A sweeping review of 41 studies, published in PLOS One, reveals a consistent and troubling pattern: women are less likely than men to receive active, invasive, or intensive medical treatment for comparable conditions. The finding held across a wide range of specialties, from cardiology to psychiatry to emergency medicine.
Researchers led by Dr. Miriam Veenhuizen of the University of St. Andrews reviewed mostly retrospective case series, with 33 of 41 studies reporting a statistically significant sex-based difference in treatment. Importantly, these disparities existed even when clinical guidelines made no distinction between male and female patients.
Key Takeaways:
Why it matters: The researchers caution that patient preference may partly explain the gap, and clinical outcomes weren't directly measured. But with AI systems increasingly trained on this same biased medical literature, the concern is that these disparities could be automated and amplified at scale if left unaddressed.