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Getting the latest healthcare news for you
Getting the latest healthcare news for you
People with more severe depression get the biggest boost from internet-based cognitive-behavioural therapy (iCBT), a new study finds — but even those with milder symptoms still improve meaningfully. Researchers warn that prediction models aren't precise enough to justify withholding iCBT from anyone. The takeaway: when in-person therapy isn't available, iCBT is a solid option across the board.
A new prognostic study published in JAMA Network Open found that patients with more severe depression at baseline benefit the most from internet-based cognitive-behavioural therapy (iCBT) — but crucially, even those predicted to benefit least still showed meaningful improvement. The study analyzed data from five randomized clinical trials across Germany and Austria, involving nearly 1,600 adults with depressive symptoms.
Researchers tested a benefit prediction model using 12 baseline factors — including depression severity, age, sex, and quality-of-life measures — to see if they could identify who should or shouldn't receive iCBT. While the model could differentiate groups by predicted benefit, it wasn't precise enough to justify selectively withholding treatment. In fact, a "treat everyone" approach consistently outperformed model-guided selective treatment.
Key Takeaways:
Why it matters: iCBT is scalable, accessible, and effective — especially where face-to-face therapy has long wait times or isn't available. This study reinforces that it should be offered broadly, even to patients with more severe depression.
