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Getting the latest healthcare news for you
Getting the latest healthcare news for you

A new study estimates that roughly 1 in 700 US women live with vulvar lichen sclerosus (VLS), a chronic inflammatory skin condition that can be seriously debilitating. Prevalence climbs sharply with age, peaking among women 70 and older, and White women bear the highest disease burden. Researchers say better awareness could support earlier diagnosis and reduce long-term risks.
A large cross-sectional study published in JAMA Dermatology puts a real number on a condition that's long flown under the radar. Vulvar lichen sclerosus (VLS) — a chronic, inflammatory skin disorder that causes itching, pain, and scarring — affects approximately 1.4 per 1,000 US women, translating to an estimated 200,000 cases nationwide. The analysis drew on data from over 740,000 women in the Explorys database between 2017 and 2019.
The condition doesn't affect all women equally. Prevalence rises steeply with age and is highest among White women, particularly those over 60. Researchers hope that quantifying this burden will push clinicians toward earlier recognition and better symptom management.
By the numbers:
Why it matters: VLS is underdiagnosed and can significantly impair quality of life — and it carries a small but real risk of vulvar cancer if left untreated. This study underscores the need for routine screening conversations, especially for older women, to catch the condition before it progresses.