Pearl Health just landed $110M to expand its AI platform for Medicare providers. The health tech startup uses predictive insights and automated workflows to help over 10,000 providers deliver proactive care to 250,000+ Medicare patients. With profitability already achieved in 2025, the company is now eyeing Medicare Advantage and projecting $500M in gross healthcare savings by 2026.
Pearl Health, a health tech startup focused on value-based Medicare care, has raised $110 million in a mix of equity and debt to scale its AI platform. The round includes $50M in equity led by Andreessen Horowitz and a $60M credit facility from Trinity Capital. The company, which reached profitability in 2025, supports over 10,000 providers across 40+ states caring for more than 250,000 Medicare beneficiaries.
The fresh capital will fuel expansion of Pearl's AI tools, including its "Performance Intelligence" platform — a natural language interface that gives care teams real-time insights on patient risk, cost of care, and quality gaps. The company is also building AI agents to automate administrative tasks like wellness visit scheduling and post-discharge follow-ups, and is now moving into Medicare Advantage.
By the Numbers:
Why it matters: With Medicare costs topping $1 trillion and reimbursement increasingly tied to outcomes, AI tools that help providers identify high-risk patients earlier and reduce avoidable costs could reshape how the system delivers — and pays for — care.
